At AstraZeneca, we turn ideas into life-changing medicines. Working here means being entrepreneurial, thinking big, and working together to make the impossible a reality. We’re passionate about the potential of science to address the unmet needs of patients around the world. We commit to those areas where we believe we can really change the course of medicine and bring big new ideas to life. Position Overview: We are seeking a highly motivated Scientist with a proven track record of scientific excellence to join our radioconjugate (RC) team in the Oncology Targeted Delivery group within AZ Early Oncology Discovery in Hamilton, Canada. You will be a key member of a team working to develop novel, targeted radioconjugate therapies and advance them through early pre-clinical development. You will bring your theoretical and practical expertise to support platform and pipeline RC projects, working with a cross-functional team to deliver pre-clinical datasets to support pipeline progression and platform development. You will have the opportunity to present data and represent the team in project team meetings, platform meetings, and other internal forums.
Responsibilities
Working in this laboratory-based position within the Early Oncology Discovery group, you will develop, invent, conduct, troubleshoot, and analyze in vitro experiments to validate tool reagents, investigate target biology, and dissect the mechanism of action of these novel cancer therapeutics. The position requires supporting cross-functional teams and working alongside project leaders to ensure the timely generation and dissemination of critical program data. As a highly organized and self-motivated person with extensive laboratory science experience, you stay current with technical and scientific expertise in tumor biology and cancer modelling. You have a genuine passion for this research area.
Requirements
Bachelor's Degree in a related field along with at least 6 years proven experience or a Master’s degree with a minimum 2 years of experience. Recent Master’s graduates with extensive prior experience in a relevant area may be eligible. Candidates who hold a Ph.D. will not qualify. Extensive knowledge of cell biology, molecular biology, and/or biochemistry in the context of cancer biology, with a desire for continued learning Deep conceptual understanding of cancer biology is preferred
Experience
with routine cell culture, particularly culture of tumor cells Expertise in molecular- and cell-based methodologies, such as cytotoxicity assays, binding and internalization assays, multicolor flow cytometry, fluorescent and live cell microscopy, ELISA, and Western blotting Candidate must work with radioisotopes with fast learning of “hot” in vitro assays Works independently with minimal direction to conduct experiments, analyze data, and prepare results for internal and external presentations and regulatory filings Excellent communication, presentation, and interpersonal skills and evidence of delivery in a team-oriented, collaborative environment Ensures own work, and work of peers, follows Good Laboratory Practice, Safety, Health, and Environment standards and all other relevant internal AstraZeneca standards and external regulations Preferred
Requirements
Background in the biopharmaceutical industry is preferable but not required
Experience
in molecular cloning and cell line engineering is highly desirable Candidates with experience related to radiation biology, radiochemistry, or radiopharmaceutical therapies would be preferable A proven record of productivity; contributions to scientific publications in peer-reviewed journals Great People want to Work with us! Find out why: GTAA Top Employer Award for 10 years Top 100 Employers Award Canada’s Most Admired Corporate Culture Learn more about working with us in Canada View our YouTube channel Are you interested in working at AZ, apply today! AstraZeneca is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. AstraZeneca is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing AZCHumanResources@astrazeneca.com. ⠀ Annual base salary for this position ranges from 82,377.60 to 108,120.60. AstraZeneca is committed to providing fair and equitable compensation opportunities to all colleagues. Our compensation policies and practices have been designed to allow colleagues to progress through the salary range over time as they progress in their role. The range provided in this posting represents an offer pay range used in a majority of situations. The base pay offered will vary depending on multiple individualized factors, including the candidate's skills and experience, job-related knowledge, and other specific business and organizational needs. In some cases, offers outside the range may also be considered to address unique circumstances. In addition, our permanent positions offer an annual Variable Pay Bonus/Short Term Incentive opportunity as well as eligibility to participate in our equity-based long-term incentive program (if applicable to role).
Benefits
offered for permanent roles include a competitive Flex
Benefits
& Retirement Savings Program, 4 weeks’ paid vacation, and annual Personal Days. Fixed Term Contract/Temporary positions (excluding students) are offered a Contract
Benefits
Program. We are using AI as part of the recruitment process. This advertisement relates to a current vacancy. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.