The Global Clinical Head (GCH) is the most senior medical scientific expert on an asset/product/indication team and is a core member of the Franchise Team (if applicable) and/or the Global Product Team (GPT). This role will report to the Vice President Clinical Respiratory. This person will be accountable for all clinical scientific aspects of the product/asset, including the benefit/risk of a product and/or asset as well as the scientific strategies for clinical components of the Target Product Profile (TPP), Target Product Claim (TPC), Clinical Development Plan (CDP), Clinical components of regulatory documents and core labelling texts. Provide clinical and medical expertise input into overall project strategy. Will have accountability for the clinical deliverables i.e. clinical studies, clinical components of regulatory submissions etc to time. Serve as the single point of contact for TA-Heads and R&D leaders for clinical and scientific components of the product and/or indications. Essential for the Role An MD, or other equivalent medical degree from an accredited university with specialty training in Respiratory or related area. Relevant experience within the respiratory space, including late-phase drug development experience. Demonstrated deep clinical and research expertise in appropriate disease area Significant hands-on late phase clinical drug development experience. Developed/delivered multiple complex and large studies (e.g., including but not limited to multinational outcome studies). Scientific credibility internally and externally. Demonstrated success in influencing functions outside of clinical and across geographies.

Experience

of benefit/risk assessment and creating patient risk management plans.

Experience

of global regulatory submissions and interacting with major regulatory agencies. Demonstrated ability to successfully lead, coach, and mentor other physicians/scientists. Proven teamwork and collaboration skills in a global setting. Credible in scientific and commercial environments. Fit for purpose business acumen, and insight into payer and reimbursement hurdles globally Line management experience. Desirable for the role Global external awareness within the therapeutic area. Global regulatory awareness. Ability to travel nationally and internationally.

Experience

in several organizations and geographic locations

Experience

of working with Market Companies to deliver studies/projects.

Experience

of clinical/commercial interface. At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, pioneering groundbreaking methods and bringing unexpected teams together. Date Posted 10-Aug-2026 Closing Date 16-Aug-2026 Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.