Typical Accountabilities · Ensure the optimal application of clinical pharmacokinetics (PK), pharmacodynamics (PD), and modelling & simulation (M&S) in clinical development programs, including: 1. Design and conduct clinical studies including CP studies (dosing rationales, sampling schemes, etc.) 2. Data analyses (e.g., M&S) to elucidate dose-exposure-response relationships, and result interpretations 3. Play a central role in justifying dose recommendations for Asian population by using quantitative approaches 4. Promote M&S approaches in clinical development programs whenever applicable 5. When applicable, develop mathematical and statistical models to understand disease mechanism, its progression, and PK/PD; conduct meta-analyses as appropriate to maximize data use. 6. Preparation and defence of regulatory submissions, as well as regulatory interactions such as end of phase consultation meetings, query response, etc. · Interact with internal and external stakeholders for assigned projects · Literature research and knowledge sharing; publish clinical pharmacology-related research articles and reviews in peer-reviewed journals, when applicable · Train junior CP staff Education, Qualifications, Skills and Experience Essential Advanced training with a degree such as PhD, PharmD, and MD to enable a successful career in the field. Applicant with a master’s degree should have a strong technical background and have been successfully delivering the drug development projects before. Experienced in drug clinical development Proficiency in oral and written mandarin and English; Capability to provide own learnings, ideas, and experiences to internal stakeholders Excellent communication, analytical and problem-solving skills Experience with both early and late phase clinical development Date Posted 06-8月-2026 Closing Date 30-12月-2026 AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.