Posted 3 days ago

Senior Forward Deployment Engineer - Cheminformatics & AI Modelling

4314 AstraZeneca Pharmaceuticals LP Company United States of America, US - Cambridge Kendall SQ - MA
Onsite Full Time

Job description

AstraZeneca are looking for a Senior Forward Deployed Engineer with a strong Chemistry Background based in our new Kendall Square R&D facilities to continue to build and enhance our next-generation multi-modality drug discovery platform. AstraZeneca has invested heavily in our Augmented Design-Make-Test-Analyze IT (A-DMTA) toolsets as we seek to deliver better, differentiated candidate drugs into trials, faster, for greater patient benefit. We have made great strides in creating an ecosystem enabling operational and experimental data capture, and in developing scaled analytics, AI/ML-enabled services, and digital capabilities for both traditional small molecules and complex modalities to drive a Predict First culture in drug discovery. We are extending these capabilities with more advanced modelling, intelligent applications, and platform engineering solutions. We are looking for a Senior Forward Deployed Engineer with a Chemistry Background to join our team and help build our integrated software platform supporting key drug discovery science. In this role you will join a global team of engineers, cheminformaticians, architects, business analysts, and product managers in our Augmented Design Make Test Analyse (A-DMTA) organisation to support small molecule and new modality drug discovery as a Senior Forward Deployed Engineer. The following will form part of the role: Partner directly with scientists, product teams, and technical stakeholders to understand high-value problems and translate them into practical engineering solutions. Design, build, deploy, and improve software applications, agentic solutions, MCP servers and tools and services that support key scientific workflows in drug discovery. Prototype rapidly, validate with users, and evolve successful solutions into robust, scalable, production-grade systems. Bridge chemistry, cheminformatics, data, and engineering to deliver integrated solutions across scientific and technical workflows. Collaborate with product, design, data science, and scientific teams to build high-impact applications and services. Plan, implement, and support platform and infrastructure development with the objective of improving scalability, reliability, performance, and usability. Advocate for rigorous engineering practices and discipline, including code reviews, automated testing, logging, monitoring, documentation, and maintainability. Help develop and promote a strong software engineering culture across multidisciplinary teams. Stay on top of relevant technology trends, experiment with new approaches, participate in internal and external technology communities, and mentor other members of the engineering community. Work with modern technology stacks in cloud environments to support scientific software delivery. Required skills Strong software engineering expertise in Python, including advanced object-oriented design and development of production-quality applications and services.

Experience

designing, building, and deploying scalable software systems, APIs, and services in production environments. Strong problem-solving and solution design skills, with the ability to translate complex scientific or business needs into practical software solutions.

Experience

working directly with users, stakeholders, or domain experts to gather requirements, refine use cases, and deliver deployed solutions. Ability to rapidly prototype solutions, validate them with users, and mature them into robust, maintainable production systems. Background in chemistry (PhD preferred, Masters essential), with experience in cheminformatics, chemistry toolkits, chemistry search, and related algorithms.

Experience

integrating systems, services, and data pipelines across complex technical environments.

Experience

with relational databases such as PostgreSQL or Oracle, and/or NoSQL technologies such as Elasticsearch.

Experience

in data analysis, including profiling, investigating, interpreting, and documenting data structures.

Experience

in performance tuning SQL and understanding ETL or data integration pipelines. Extensive experience troubleshooting data issues, analysing end-to-end data pipelines, and improving application or service performance. Good experience in consuming or exposing web APIs.

Experience

designing, developing, and deploying production-grade scalable applications using container technologies like Docker and Kubernetes. Production experience delivering CI/CD pipelines using tools such as GitHub Actions, ArgoCD, or similar.

Experience

creating and evaluating engineering architecture in the cloud. Excellent verbal and written communication skills for effective collaboration with engineers, testers, architects, product managers, scientists, and other stakeholders. Ability to work effectively in fast-moving and ambiguous environments, with ownership of delivery from problem definition through deployment and iteration. The following skills would be advantageous for your application but are not considered essential:

Experience

working with AWS. DevOps experience, including deployment workflows and monitoring tools such as Grafana, Prometheus, and GitHub Actions. Working knowledge of Scrum or Agile delivery. Product ownership or technical leadership experience, with strong stakeholder communication and management. Exposure to AI/ML-enabled applications in production, particularly where these are embedded within broader scientific or engineering platforms. Development of agentic systems, MCP servers or tools Specification-driven development The annual base pay (or hourly rate of compensation) for this position ranges from $144,648.80 - 216,973.20 USD Annual. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles.

Benefits

offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans. Date Posted 12-ago-2026 Closing Date 10-sept-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.

Skills and functions

  • Aws
  • Data Science
  • Kubernetes
  • Python
  • Software Engineering
  • Sql