The Role The Principal Data Architect will design and steward the enterprise data architecture that makes CMC data usable, governable, and AI-ready at scale. This role defines integration patterns, data models, metadata standards, and reusable architecture artifacts that enable consistent, scalable delivery of data products across Manufacturing, Quality, and Supply Chain operations. A core focus is enabling the integration of real-time data from control systems and automation environments into a unified, event-driven architecture that bridges OT and IT data, requiring deep understanding of manufacturing and automation processes. CMC data spans systems with diverse structures, semantics, and quality characteristics. This role brings coherence to that complexity by designing patterns that normalize heterogeneous data into a platform where analysts, engineers, and AI systems can operate with confidence. As a principal-level contributor, this individual operates with significant autonomy, influences technical direction across CMC Digital, and builds the architectural foundations that enable consistent, reusable, and scalable data and AI capabilities across the enterprise. Here’s What You’ll Do · Define and maintain the target-state data architecture across CMC domains, designing for composability with shared entities modeled once and domain-specific extensions layered on top · Define and implement integration patterns that connect control systems and automation environments with enterprise data platforms, enabling real-time, event-driven data flows across OT and IT layers · Establish repeatable patterns for ingesting, transforming, and serving data from heterogeneous CMC systems · Define and enforce data standards, including naming conventions, classification, lineage, and metadata, treating metadata as a first-class architectural concern · Design data models and semantic structures that support both analytics and AI use cases across CMC domains · Codify architecture patterns as templates, reference implementations, and decision records, enabling teams to build from proven designs rather than starting from scratch · Develop strategies for controlled vocabularies, business glossaries, and semantic models that make CMC data consistent and navigable across domains · Inform cloud data platform decisions across warehousing, transformation, orchestration, and catalog tooling to ensure alignment with architectural standards · Mentor engineers and data product owners, raising architectural fluency and design consistency across the CMC Digital organization Here’s What You’ll Need (Basic Qualifications) · Bachelor’s or Master’s degree in Computer Science, Engineering, Data Science, or a related field · 7+ years of experience in data architecture, data engineering, or enterprise architecture · 4+ years of experience supporting pharmaceutical, biotech, manufacturing, or other regulated environments ·
Experience
integrating data from control systems, automation environments, or real-time operational data sources ·
Experience
designing data architectures that span operational systems and analytical platforms, connecting source systems to governed, reusable data products · Integration architecture experience across enterprise systems, including ERP, QMS, MES, LIMS, or equivalent · Strong understanding of data modeling, both dimensional and entity-relationship approaches, applied to operational and analytical use cases · Proven ability to produce architecture specifications that engineering teams can implement directly · Strong understanding of data governance mechanics, including lineage, access control, data classification, and retention · Understanding of GxP, data integrity, and compliance considerations and how they shape architectural decisions Here’s What You’ll Bring to the Table (Preferred Qualifications) · Direct experience with Veeva Quality, LabVantage, Syncade, or similar MES and LIMS platforms and their data structures ·
Experience
with OT/IT integration architecture, including MES, DCS, SCADA, or historian systems in a regulated environment · Familiarity with manufacturing data standards and how they inform enterprise data architecture decisions ·
Experience
with SAP data domains and integration patterns for manufacturing and supply chain data · Hands-on experience with dbt, Redshift, Snowflake, or similar transformation and cloud data warehouse tooling ·
Experience
with metadata management, data catalog tooling, or business glossary programs at enterprise scale ·
Experience
designing multi-schema or multi-tenant architectures with fine-grained, policy-driven access control · Exposure to knowledge graphs, ontologies, or semantic modeling applied to enterprise or scientific data ·
Experience
with GitHub-based workflows, architecture-as-code practices, or version-controlled specification and pattern management ·
Experience
with or strong interest in AI-ready data architecture, including how data models, semantic layers, and operational knowledge bases support agentic AI workflows · Background in GxP validation readiness for data platforms and how architectural decisions affect future compliance posture Pay &
Benefits
At Moderna, we believe that when you feel your best, you can do your best work. That’s why our benefits and well-being resources are designed to support you—at work, at home, and everywhere in between. Competitive healthcare, plus voluntary benefit programs to support your unique needs A holistic approach to well-being, with access to fitness, mindfulness, and mental health support Family planning benefits, including fertility, adoption, and surrogacy support Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown Savings and investments to help you plan for the future Location-specific perks and extras The salary range for this role is $145,900.00 - $234,200.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual’s position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs. The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance. About Moderna Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. Our Working Model As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact. Moderna is a smoke-free, alcohol-free, and drug-free work environment. Equal Opportunities Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is a place where everyone can grow. If you meet the Basic
Qualifications
for the role and you would be excited to contribute to our mission every day, please apply! Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements. Accommodations We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at leavesandaccommodations@modernatx.com. Export Control Notice This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant’s ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license. #LI-KH1 - Our Mission and Vision At Moderna we are pioneering the development of a new class of drugs made of messenger RNA (mRNA). This novel drug platform builds on the discovery that modified mRNA can direct the body’s cellular machinery to produce nearly any protein of interest, from native proteins to antibodies and other entirely novel protein constructs that can have therapeutic activity inside and outside of cells. We have a clear mission to propel the field of mRNA science forward and deliver new medicines to patients and a unique vision for how to achieve this mission. Our Mission: To deliver on the promise of transformative messenger RNA (mRNA) science to bring new medicines to patients. Our Vision: To unlock the potential of mRNA by establishing an ecosystem of teams and partners that will work together to develop the broadest possible array of drugs, across diverse therapeutic areas and routes of administration, for serious diseases that are not treatable today. Third Party Staffing Agencies Moderna does not accept unsolicited resumes from any source other than directly from candidates. For the protection of all parties involved in the recruiting process, resumes will only be accepted from recruiters/agencies if a signed agreement is in place at the inception of the recruiting effort and authorized for a specified position. Unsolicited resumes sent to Moderna from recruiters/agencies do not constitute any type of relationship between the recruiter/agency and Moderna and do not obligate Moderna to pay fees if we hire from those resumes. Reasonable Accommodation Notice Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Applicants with disabilities may be entitled to reasonable accommodation under the terms of the Americans with Disabilities Act and certain state or local laws. Please inform the company's personnel representative by calling 617-460-9346 or emailing humanresources@modernatx.com if you need assistance completing any forms or to otherwise participate in the application process. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment. Return Home