Job Description: The Head of Medical Excellence, US BBU, is a highly influential leadership role with the opportunity to build and shape a newly established capability that will transform how Medical Affairs delivers value across the portfolio. This leader will set the vision and operating model for Medical Excellence, strengthening the quality, consistency, innovation, and measurable impact of scientific engagement. Reporting to the VP, US Medical Affairs, this person will lead an integrated team spanning Digital Medical Strategy and Innovation, Customer Engagement, Scientific Communications, Medical Informatics, Medical Training, and the Medical

Education

and Grants Office. Working across science, strategy, data, and technology, they will enable medical teams to engage customers more effectively, translate insights into action, and improve access to relevant medical information. Accountabilities Digital Medical Strategy and Innovation: Set the vision and strategic framework for digitally enabled Medical Affairs across the US BBU. Lead the evaluation, prioritization, and scaled adoption of innovative channels, technologies, and operating models that strengthen scientific exchange, improve access to medical information, and deliver measurable value for healthcare professionals and patients. Customer Engagement: Define a coordinated, customer-centric engagement model across Medical Affairs that connects field, digital, and other channels. Establish customer experience standards and use engagement insights to improve the relevance, consistency, and effectiveness of scientific interactions. Serve as point of contact for congress planning for medical US BBU (in collaboration with the Commercial function and Global Medical) Scientific Communications Define and lead the US scientific communications strategy and execution across therapeutic areas, portfolios, aligned with broader medical strategy. Medical Informatics: Lead the strategy, governance, accountability and enablement of medical data, analytics, and technology across the US BBU. Ensure medical teams have timely access to high-quality, actionable information and analytics, while advancing interoperability, data stewardship, compliant use, and the translation of insights into decisions and improved medical execution. This includes responsibility of medical analytics; thought leader framework and segmentation; enablement of tools and platforms(future of CRM, Salesforce, Veeva, and ATLAS) and define and deliver standardized metrics, OKR/KPI reporting, dashboards and actionable insights. Medical

Education

and Grants Office (MEGO): Lead the strategy, governance, and operational excellence for independent medical education and medical grants across the business. Establish clear standards for the intake, review, funding, oversight, and impact assessment of grant requests, ensuring decisions are objective, compliant, transparent, and aligned with identified educational needs and Medical Affairs priorities. Scientific Training Strategy & Delivery: Own the global scientific learning strategy across the portfolio, including disease, product, and evidence curricula. Oversee onboarding, core academies, and continuing education using modern learning approaches to ensure proficiency and retention. Field Medical Excellence: partner wirh GMA and Field Leadership to set standards for Field Medical roles, scientific exchange, insight generation, and cross-functional collaboration to support consistent, high-quality, and compliant external engagement. Governance, Quality & Compliance: Ensure training, materials, and Field Medical practices align with global and local regulations and internal standards. Support governance forums and maintain audit readiness. Accountable for developing a high-performing team, fostering a culture of performance development, accountability inclusion, and diversity. Model and reinforce the ethical, quality, and compliance standards required by the US organization. Essential Skills/

Experience

Advanced scientific, clinical, education, or business degree (e.g., PharmD, PhD, MD, EdD, MS, MBA). A minimum of 10 years in Medical Affairs in pharma with dynamic leadership across global and regional roles. Deep knowledge of the drug development process and stakeholder landscape. Deep understanding of scientific exchange principles, external partner engagement, and compliance frameworks across US. Expertise with digital/omni-channel medical and analytics. Demonstrates critical thinking, enterprise approach, change leadership, influence at senior levels, people development, and matrix leadership across geographies and cultures. Experienced with CRM and insights systems, LMS/LXP platforms, content management, critical metric dashboarding/BI tools; ability to interpret data and translate into actions. High ethical standards and dedication to compliance, patient-centricity, and quality. Desirable Skills/

Experience

Direct experience building medical capabilities and MSL organizations; proven track record in scientific training design and delivery; experience establishing and scaling impact metrics and dashboards. Visionary leadership with enterprise perspective Significant matrix-team leadership experience. Scientific rigor paired with digital proficiency and pragmatic execution. Change leadership and adoption excellence across matrixed environments. At AstraZeneca, you get to Embrace the opportunity to shape the future of healthcare. Be part of changing the practice of medicine forever. A place to be at the forefront; proactive, innovative and brave, we don’t stop. The annual base pay for this position ranges from $285,872 to $428,809 Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles).

Benefits

offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. Date Posted 07-Aug-2026 Closing Date 23-Aug-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.