Location: Wilmington Hybrid: 3 Days a week At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big, and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person. About the Role The Senior Medical Director, Hypertension shapes product and disease area strategy, provides strategic direction for evidence generation, education and publication, and engages extensively externally to further the scientific leadership of AZ. It is a key scientific role that reports directly to the Medical Head – Hypertension, within the BioPharmaceuticals Business Unit’s US Medical CVRM franchise. What you’ll do: Provide medical leadership and subject matter expertise for the creation, delivery and evolution of disease area and brand strategies and plans Build external collaborations (e.g. relationships with KEEs, investigators, scientific associations, digital therapeutics/diagnostics partners) and seek and incorporate external advice to drive strategy Lead the product and disease area Advisory Board strategy Lead the product and disease area Externally Sponsored Research (ESR) program Shape and drive strategic publications plans and evidence-generation initiatives Provide medical leadership and subject matter expertise for regulatory and labelling interactions Through partnership and innovative thinking, anticipate future trends and needs in the marketplace Essential for the role: MD, PhD, or PharmD Medical/clinical/scientific expertise in CVRM 5+ years of experience in the pharmaceutical industry, ideally in Medical Affairs or relevant years of experience in the Medical / Healthcare field Strategic and innovative thinker with an executive presence Demonstrated track record delivering results in a complex matrix environment, building capabilities, and leading large-scale impactful medical initiatives Proven ability to collaborate and build internal and external networks Strong analytical mindset and ability to quickly assess large amounts of information and distil into key messages and actions Experience and/or appreciation of product launches and product life cycle management Persuasive oral and written communication skills, including the ability to develop and deliver impactful presentations Proven ability to collaborate with individuals of diverse experience and backgrounds, across varying functions, levels within the company, or external organizations, to effectively deliver on goals Strong business acumen, familiarity with the US healthcare system, and key regulations in the pharmaceutical industry The annual base pay for this position ranges from $243,586.40 - $365,379.60 USD Annual USD Annual and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. Apply Now! Date Posted 17-Aug-2026 Closing Date 27-Aug-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.