Are you ready to harness evidence and scientific leadership to change how breast cancer is treated worldwide? This is a high-impact role for a strategist who can turn complex science into clear, confident action that improves patient outcomes and accelerates launches across markets. As the accountable global medical leader for assigned breast cancer indication(s) and asset(s), you will own the Global Medical Strategy, bridge Research & Development with Commercial, and steer end-to-end launch readiness. Your work will close care gaps, promote health equity, and elevate scientific leadership—so physicians, systems, and patients can confidently adopt new standards of care. You will lead with accountability while empowering specialized teams to execute at pace. In an open, inclusive environment that values brave, well-reasoned ideas and attentive listening, your perspective will shape decisions that matter. Accountabilities: Global Medical Strategy and Launch Excellence: Own and deliver the Global Medical Plan for assigned breast cancer indication(s)/asset(s), setting direction, prioritizing initiatives, and making evidence-based trade-offs to maximize patient and business impact. Define and track clear launch and medical KPIs to diagnose progress and remove barriers to success; proactively adapt strategy to external dynamics and insights. Represent Global Medical on the Integrated Business Team (IBT) and Global Product Team (GPT) to shape Commercial strategy, inform development and lifecycle planning, and align on Target Product Profiles. Lead Medical Integrated Teams (MITs) to align global, regional, and country execution; represent Medical in Launch Readiness and Strategic Brand Reviews to elevate Medical Affairs’ role and impact. Influence clinical development and commercialization strategies, ensuring medical needs, evidence gaps, and companion study requirements are addressed early and decisively. Evidence Generation and Dissemination: Lead global and regional gap assessments across clinical, real-world, diagnostic, and mechanistic evidence; build integrated, cross-functional evidence plans that enable confident adoption and guideline inclusion. Shape the scientific and strategic design of Medical Affairs interventional studies; conceptualize and align real-world evidence programs with broader strategy; govern milestones, resources, and standards. Own the Global Publications Plan from late-phase development onward; ensure timely, credible, and compliant scientific communications that build trust with external experts and decision-makers. Champion innovative approaches—leveraging networks, novel study designs, and data-driven insights—to generate transformative evidence that changes practice. Confidence Building and External Engagement: Lead the scientific narrative from four months prior to Phase 3 investment decision, ensuring consistency across evidence, publications, congresses, and education. Build accountability for an Integrated Confidence Plan while partnering with centers of excellence for execution; define priority audiences, learning objectives, and delivery formats. Shape external engagement strategies with key experts, societies, health systems, and global organizations; gather actionable insights and actively influence to accelerate guideline adoption and health outcomes. Lead congress strategy end to end, including pre-congress abstracts and training, and post-congress insight synthesis and dissemination. Capability Building and Enterprise Leadership: Coach, delegate, and empower global medical teams to strengthen capabilities; model enterprise leadership that drives alignment, pace, and a culture of scientific excellence and collaboration. Essential Skills/

Experience

Advanced degree required (MD, PhD, PharmD, or equivalent scientific degree). Significant experience in Medical Affairs (~ 10 yrs) within the pharmaceutical or biotech industry, ideally at the country, Region and global level. Demonstrated success in leading evidence generation strategies, Medical Plans, publications, or scientific communication programs. Proven ability to influence senior stakeholders across Commercial, R&D, and Medical Affairs.

Experience

engaging external experts and scientific communities Desirable Skills/

Experience

Previous global Medical Affairs leadership experience in oncology.

Experience

leading crossfunctional teams in highly complex, multiindication environments.

Experience

navigating launch environments, new MoAs, new CDx, complex biomarker landscapes, or challenging safety profiles (aligning to GMAL complexity criteria). When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. Why AstraZeneca: Here, science and strategy meet at scale to transform cancer care. You will work with colleagues across disciplines—data, development, medical, and commercial—translating evidence into clinical practice and impacting every step of the patient journey. We move with urgency, value kindness alongside ambition, and create space for brave ideas that are heard and acted on. Surrounded by a deep pipeline and cutting-edge tools in real-world evidence and analytics, your leadership will help turn compelling data into new standards of care for people living with breast cancer. Call to Action: If you are ready to lead global medical strategy and deliver launches that change practice and improve lives, take the next step today and help shape the future of breast cancer treatment! The annual base pay for this position ranges from $ 193,281 - 289,922 USD. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program.

Benefits

offered include a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors Date Posted 17-Aug-2026 Closing Date 27-Aug-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.